![]() I don't think I have ever actually taken this mutation in a speedrun before, because it just doesn't seem very beneficial. It cuts a bunch of your time from your run, and it negates spider webs in the caves, which is very important. In all honesty though, this is probably the 2nd best mutation in the entire game for speedrunning. This gives you more speed, pretty easy pick here. When combined with Eyes, it does become more useful, but there are still plenty of other things I would take over this mutation, even as Eyes.Ĭ'mon guys, it's a speedrun. The only person who actually shoots fast enough for it to be a concern is Lil' Hunter, and even then it doesn't help much with that fight. So the question is, is it worth it? Probably not. If you manage to pick up something with a huge shot spread like a triple machine gun or a minigun, this ends up being a disgusting combo. So, there are scenarios that make Eagle Eyes the best mutation in the game, and many more scenarios that make it useless. Also not that great with disc guns.Įagle Eyes - 2 (5 if you get the right weapon) This is essential for any run that is using a bolt weapon. The ability to kill a room full of weak guys with 1 shot is insane. However, when you do have a bolt weapon, this kicks ass. Generally speaking, it is not worth the risk of taking this mutation without a weapon that benefits from it. Unfortunately, in the grand scheme of things,this doesn't really help much to make your run faster, just safer, so it only gets a 3.īolt Marrow - 3 (5 if you have a bolt weapon) Not only will this mutation allow you to hit things at close range, but it saves you from things like car explosions, those suicide bombers in the labs, and it allows you to essentially stand on top of the throne when it explodes, cutting a second or two from your time. While explosions are great for killing large groups of weak enemies and can still kill a single high hp target without much trouble, the fact that they cannot kill anything at close range without killing you is a huge downside. Personally, I despise using explosive weapons. It doesn't really make you win any faster, so it is essentially a waste of a slot. Picking this up early can usually lead to you having an ammo supply higher than your previous maximum capacity, but that will generally be depleted fairly quickly, making it dead weight for what could be a much faster run if another mutation was taken instead.īloodlust offers us a decent amount of survivability, but at the cost of an uncontrollable negative synergy with Stress. Having a huge stockpile of ammo is essential for lasting as long as possible, but that is not our goal here. So many people love this mutation when playing to loop. If you only have mutations that are 3 and lower, go for Patience and hope for the best.Ĥ. Essentially, if you have anything at 4 or higher, take that instead of Patience. I believe Patience is a very important mutation, and I'm sure most of you will find yourselves taking it very often. If you get this on your first level in a 1 Character run, I would probably reset unless I have some really good weapons.ģ.5. It is a definite benefit to your run, but there is still probably better. Only helps slightly, and should probably be ignored as well.ģ. The proper utilization of this mutation will most likely cost you time.Ģ. To get a better idea of this rating scaleġ. This will be in alphabetical order, and each mutation will be given a rating from 1-5. With that in mind, I want to analyze each mutation and determine how useful it would be in a speedrun. I am a believer that having good mutation RNG is one of the most important factors to having a fast run, maybe even more important than good weapon RNG. I figured it would be important to have a few tips for new players, so here we are. Hello, and welcome to a guide on mutations.
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